New research points to a possible link between autism spectrum disorder (ASD) and the gut microbiota as many autistic children have co-occurring gastrointestinal problems. Various altered metabolite levels were observed in the blood and urine of autistic children, many of which were of bacterial origin such as short chain fatty acids (SCFAs), indoles and lipopolysaccharides (LPS). […] The frequently reported comorbidity of GI problems in autistic children [1,14,15,16,17,18,19] motivated the central question of this review: is there a connection between the gut microbiota and the central nervous system (CNS) affecting the pathology of ASD?

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